📄 Category

geriatric medicine

13 papers

Geriatric medicine focuses on the unique health needs of older adults, addressing complex conditions that often arise as we age. This field goes beyond treating single diseases to manage the whole person, considering how multiple chronic issues, medication interactions, and physical changes affect quality of life. By prioritizing functional ability and dignity, researchers in this space aim to help people live healthier, more independent lives for as long as possible.

Gist.Science makes the latest findings in this vital area accessible by processing every new preprint from medRxiv in this category. We transform these raw scientific reports into both plain-language overviews for general readers and detailed technical summaries for specialists, ensuring no one is left behind by complex jargon. Below are the latest papers in geriatric medicine, updated regularly as new research becomes available on medRxiv.

Interest in and feasibility of a dementia prevention program among community-dwelling older adults: a questionnaire survey

This questionnaire survey of nearly 10,000 Japanese older adults reveals that while there is moderate interest in dementia prevention programs—particularly those offering short, 10-minute activities—awareness remains low and individuals with frailty or subjective cognitive decline are less likely to engage, highlighting the need for proactive outreach strategies to bridge the evidence-practice gap.

Kouzuki, M., Tazumi, H., Nakada, N.2026-03-24📄 geriatric medicine

REPROGRAM: REsilience PROmotion with GeRoprotectors: AssessMent of biological effect. Rationale and protocol for a trial of biological effect.

The REPROGRAM trial is a randomized study designed to assess whether a three-week course of the geroprotectors Metformin, Fisetin, or Spermidin can reduce senescent cells and reverse other hallmarks of ageing in 60 healthy adults aged 70 and older.

Wilson, D., Acharjee, A., Duggal, N. A., Hombrebueno, J. R., Jones, S. W., Lewis, J. W., de Magalhaes, J. P., Martinez-Serrato, Y. P., Mazaheri, A., McGettrick, H. M., Mondal, S. M., Naylor, A. J., Ni (…)2026-03-23📄 geriatric medicine

Development of a Multi-Trait Polygenic Score for Intrinsic Capacity

This study developed and validated a multi-trait polygenic score for intrinsic capacity using data from over 13,000 Canadian participants, demonstrating that a model integrating genetic predictors across five domains effectively captures the multisystem biological basis of healthy aging and is significantly associated with reduced mortality.

Beyene, M. B., Visvanathan, R., Alemu, R., Sharew, N. T., Theou, O., Benyamin, B., Cesari, M., Beard, J., Amare, A. T., Amare, A. T.2026-02-27📄 geriatric medicine